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The total quantity of MDMA consumed in Europe is reached by multiplying the number of users by the amount used, combining prevalence data from general population surveys and the amount used from the EWSD.
However, from 2019 onwards, the quantity of MDMA found in tablets appears to have slightly decreased. However, larger seizures of these mixtures have also been reported in the European Union. These detections have generally been small in quantity with the powders containing a range of different substances – always ketamine and MDMA, and typically additional substances including cocaine, caffeine or cathinones. The majority of these identifications were reported by Spain, although pink powders have also been reported in Czechia, Germany, Estonia, Hungary, the Netherlands, Austria, Poland, Romania, Sweden and Norway. Throughout 2021, and continuing into 2022 and 2023, a number of detections of pink powders consistent with tucibi were reported to the EU Early Warning System. Tuci or tucibi (also spelled tusi and tusibi) are phonetic transliterations of ‘2C’ (a series of psychoactive phenethylamines) or ‘2C-B’ (one of the most well-known derivatives of that series of substances).
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Data collected from individuals submitting MDMA samples to drug-checking services between 2019 and 2022 appear to support these findings from the EWSD. For example, 79 % of the Polish respondents reported mostly buying the drug, compared to 51 % of the respondents from Luxembourg. Data from drug-checking services can also inform on the type of relationships that exist between the consumer and the provider. Web-based surveys, such as the EWSD, can provide a helpful insight, although the results cannot be generalised to the population as a whole, or indeed to all people who use drugs. For example, alcoholic drinks containing MDMA are submitted for drug checking from time to time. Samples submitted to drug-checking services Going At this website can also provide an indication of the products available to consumers.
Ecstasy adulteration is responsive to market pressures
According to 2021 data, tablets and powders/crystals share the EU MDMA market equally, with some variability among countries in terms of preference for either ecstasy tablets or MDMA powders/crystals (see Figure 6.1. Distribution of usual MDMA forms across countries). In the Netherlands, Going At this website in 2022, the price of 1 kilogram of (locally produced) MDMA crystals was reported at EUR 2 300, whereas 1 litre of MDMA oil (which can be converted into crystals or powder, and subsequently ecstasy tablets) was reported at EUR per litre. For the six countries that reported data for 2022, prices for tablets varied from EUR 733 to EUR 7 228. Tablets containing more than 150 milligrams of MDMA are considered high-strength ecstasy tablets, given the dose of MDMA required to elicit subjective effects in adults (a). On occasion, exceptionally high-strength ecstasy tablets were reported, reaching upwards of 250 milligrams of MDMA per tablet, which made up 1 % of all tablets tested in 2023 (3 % in the same period in 2022). In 2023, 39 % of the MDMA tablets tested by drug checking organisations submitting data to the TEDI network contained between 100 and 149.0 milligrams of MDMA (35 % in the same period in 2022), and 26 % contained between 150 and 199.9 milligrams (29 % in 2022
Other drugs and ‘fillers’ are often used instead. MDMA is commonly known as ecstasy.2 However, some pills sold as ecstasy may only have a small amount of MDMA or none at all. But being able to web-scrape and analyze data from cryptomarkets has tremendously improved understanding of these markets. The full impact of the "dark web" on the illicit drugs trade remains inconclusiv
Some of the price disparity may be attributed to local factors, including distance to the producing centres (Netherlands and Belgium), but statistical artefacts (e.g. small sample sizes) may also be a factor. Individual factors and sex affect this dose, with women considered to be more susceptible to the 5-HT-releasing effects of MDMA (Liechti et al., 2001). Harm reduction responses, including the provision of drug-checking services and appropriate risk-communication strategies, are crucial to minimise these risks. This is consistent with law enforcement information that suggests the MDMA market in Europe is supplied by the same pool of producers, mostly based in the Netherlands and Belgium. It should be noted that this trend was observed across several countries in Europ
(a) In clinical trials, doses of MDMA capable of producing subjective effects vary from 1.5 to 1.7 mg/kg of body weight, or approximately 105 to 119 milligrams for a 70-kilogram individual. Some tablets even contain stamping that indicate the quantity of MDMA present, although this is not always accurate and may also constitute a health risk. For example, in August 2023, tablets containing 350 milligrams of MDMA were seized in Spain. Meanwhile, data from drug-checking services suggest that approximately 85 % of the powders tested in 2023 contained between 80 and 100 % MDMA (81 % in 2022). Data reported to drug-checking services are generally in agreement with these trend